Objectives: Timely and accurate detection of colorectal polyps plays a crucial role in diagnosing and preventing colorectal cancer, a major cause of mortality worldwide. This study introduces a new, lightweight, and efficient framework for polyp detection that combines the Local Outlier Factor (LOF) algorithm for filtering noisy data with the YOLO-v11n deep learning model. Study design: An experimental study leveraging deep learning and outlier removal techniques across multiple public datasets. Methods: The proposed approach was tested on five diverse and publicly available datasets: CVC-ColonDB, CVC-ClinicDB, Kvasir-SEG, ETIS, and EndoScene. Since these datasets originally lacked bounding box annotations, we converted their segmentation masks into suitable detection labels. To enhance the robustness and generalizability of our model, we apply 5-fold cross-validation and remove anomalous samples using the LOF method configured with 30 neighbors and a contamination ratio of 5%. Cleaned data are then fed into YOLO-v11n, a fast and resource-efficient object detection architecture optimized for real-time applications. We train the model using a combination of modern augmentation strategies to improve detection accuracy under diverse conditions. Results: Our approach significantly improves polyp localization performance, achieving a precision of 95.83%, recall of 91.85%, F1-score of 93.48%, mAP@0.5 of 96.48%, and mAP@0.5:0.95 of 77.75%. Compared to previous YOLO-based methods, our model demonstrates enhanced accuracy and efficiency. Conclusions: These results suggest that the proposed method is well-suited for real-time colonoscopy support in clinical settings. Overall, the study underscores how crucial data preprocessing and model efficiency are when designing effective AI systems for medical imaging.

Image contrast was a fundamental factor in visual perception and played a vital role in overall image quality. However, most no reference image quality assessment NR IQA models struggled to accurately evaluate contrast distortions under diverse real world conditions. In this study, we proposed a deep learning based framework for blind contrast quality assessment by customizing and fine-tuning three pre trained architectures, EfficientNet B0, ResNet18, and MobileNetV2, for perceptual Mean Opinion Score, along with an additional model built on a Siamese network, which indicated a limited ability to capture perceptual contrast distortions. Each model is modified with a contrast-aware regression head and trained end to end using targeted data augmentations on two benchmark datasets, CID2013 and CCID2014, containing synthetic and authentic contrast distortions. Performance is evaluated using Pearson Linear Correlation Coefficient and Spearman Rank Order Correlation Coefficient, which assess the alignment between predicted and human rated scores. Among these three models, our customized EfficientNet B0 model achieved state-of-the-art performance with PLCC = 0.9286 and SRCC = 0.9178 on CCID2014 and PLCC = 0.9581 and SRCC = 0.9369 on CID2013, surpassing traditional methods and outperforming other deep baselines. These results highlighted the models robustness and effectiveness in capturing perceptual contrast distortion. Overall, the proposed method demonstrated that contrast aware adaptation of lightweight pre trained networks can yield a high performing, scalable solution for no reference contrast quality assessment suitable for real time and resource constrained applications.

Accurate prediction of molecular solubility is a cornerstone of early-stage drug discovery, yet conventional machine learning models face significant challenges due to limited labeled data and the high-dimensional nature of molecular descriptors. To address these issues, we propose LatMixSol, a novel latent space augmentation framework that combines autoencoder-based feature compression with guided interpolation to enrich training data. Our approach first encodes molecular descriptors into a low-dimensional latent space using a two-layer autoencoder. Spectral clustering is then applied to group chemically similar molecules, enabling targeted MixUp-style interpolation within clusters. Synthetic samples are generated by blending latent vectors of cluster members and decoding them back to the original feature space. Evaluated on the Huuskonen solubility benchmark, LatMixSol demonstrates consistent improvements across three of four gradient-boosted regressors (CatBoost, LightGBM, HistGradientBoosting), achieving RMSE reductions of 3.2-7.6% and R-squared increases of 0.5-1.5%. Notably, HistGradientBoosting shows the most significant enhancement with a 7.6% RMSE improvement. Our analysis confirms that cluster-guided latent space augmentation preserves chemical validity while expanding dataset diversity, offering a computationally efficient strategy to enhance predictive models in resource-constrained drug discovery pipelines.

Breast cancer stands as a prevalent cause of fatality among females on a global scale, with prompt detection playing a pivotal role in diminishing mortality rates. The utilization of ultrasound scans in the BUSI dataset for medical imagery pertaining to breast cancer has exhibited commendable segmentation outcomes through the application of UNet and UNet++ networks. Nevertheless, a notable drawback of these models resides in their inattention towards the temporal aspects embedded within the images. This research endeavors to enrich the UNet++ architecture by integrating LSTM layers and self-attention mechanisms to exploit temporal characteristics for segmentation purposes. Furthermore, the incorporation of a Multiscale Feature Extraction Module aims to grasp varied scale features within the UNet++. Through the amalgamation of our proposed methodology with data augmentation on the BUSI with GT dataset, an accuracy rate of 98.88%, specificity of 99.53%, precision of 95.34%, sensitivity of 91.20%, F1-score of 93.74, and Dice coefficient of 92.74% are achieved. These findings demonstrate competitiveness with cutting-edge techniques outlined in existing literature.

Human brain neuron activities are incredibly significant nowadays. Neuronal behavior is assessed by analyzing signal data such as electroencephalography (EEG), which can offer scientists valuable information about diseases and human-computer interaction. One of the difficulties researchers confront while evaluating these signals is the existence of large volumes of spike data. Spikes are some considerable parts of signal data that can happen as a consequence of vital biomarkers or physical issues such as electrode movements. Hence, distinguishing types of spikes is important. From this spot, the spike classification concept commences. Previously, researchers classified spikes manually. The manual classification was not precise enough as it involves extensive analysis. Consequently, Artificial Intelligence (AI) was introduced into neuroscience to assist clinicians in classifying spikes correctly. This review discusses the importance and use of AI in spike classification, focusing on the recognition of neural activity noises. The task is divided into three main components: preprocessing, classification, and evaluation. Existing methods are introduced and their importance is determined. The review also highlights the need for more efficient algorithms. The primary goal is to provide a perspective on spike classification for future research and provide a comprehensive understanding of the methodologies and issues involved. The review organizes materials in the spike classification field for future studies. In this work, numerous studies were extracted from different databases. The PRISMA-related research guidelines were then used to choose papers. Then, research studies based on spike classification using machine learning and deep learning approaches with effective preprocessing were selected.

The Complex Emotion Recognition System (CERS) deciphers complex emotional states by examining combinations of basic emotions expressed, their interconnections, and the dynamic variations. Through the utilization of advanced algorithms, CERS provides profound insights into emotional dynamics, facilitating a nuanced understanding and customized responses. The attainment of such a level of emotional recognition in machines necessitates the knowledge distillation and the comprehension of novel concepts akin to human cognition. The development of AI systems for discerning complex emotions poses a substantial challenge with significant implications for affective computing. Furthermore, obtaining a sizable dataset for CERS proves to be a daunting task due to the intricacies involved in capturing subtle emotions, necessitating specialized methods for data collection and processing. Incorporating physiological signals such as Electrocardiogram (ECG) and Electroencephalogram (EEG) can notably enhance CERS by furnishing valuable insights into the user's emotional state, enhancing the quality of datasets, and fortifying system dependability. A comprehensive literature review was conducted in this study to assess the efficacy of machine learning, deep learning, and meta-learning approaches in both basic and complex emotion recognition utilizing EEG, ECG signals, and facial expression datasets. The chosen research papers offer perspectives on potential applications, clinical implications, and results of CERSs, with the objective of promoting their acceptance and integration into clinical decision-making processes. This study highlights research gaps and challenges in understanding CERSs, encouraging further investigation by relevant studies and organizations. Lastly, the significance of meta-learning approaches in improving CERS performance and guiding future research endeavors is underscored.

Trusting the accuracy of data inputted on online platforms can be difficult due to the possibility of malicious websites gathering information for unlawful reasons. Analyzing each website individually becomes challenging with the presence of such malicious sites, making it hard to efficiently list all Uniform Resource Locators (URLs) on a blacklist. This ongoing challenge emphasizes the crucial need for strong security measures to safeguard against potential threats and unauthorized data collection. To detect the risk posed by malicious websites, it is proposed to utilize Machine Learning (ML)-based techniques. To this, we used several ML techniques such as Hist Gradient Boosting Classifier (HGBC), K-Nearest Neighbor (KNN), Logistic Regression (LR), Decision Tree (DT), Random Forest (RF), Multi-Layer Perceptron (MLP), Light Gradient Boosting Machine (LGBM), and Support Vector Machine (SVM) for detection of the benign and malicious website dataset. The dataset used contains 1781 records of malicious and benign website data with 13 features. First, we investigated missing value imputation on the dataset. Then, we normalized this data by scaling to a range of zero and one. Next, we utilized the Synthetic Minority Oversampling Technique (SMOTE) to balance the training data since the data set was unbalanced. After that, we applied ML algorithms to the balanced training set. Meanwhile, all algorithms were optimized based on grid search. Finally, the models were evaluated based on accuracy, precision, recall, F1 score, and the Area Under the Curve (AUC) metrics. The results demonstrated that the HGBC classifier has the best performance in terms of the mentioned metrics compared to the other classifiers.

SARS-CoV-2, the highly contagious pathogen responsible for the COVID-19 pandemic, has persistent effects that begin four weeks after initial infection and last for an undetermined duration. These chronic effects are more harmful than acute ones. This review explores the long-term impact of the virus on various human organs, including the pulmonary, cardiovascular, neurological, reproductive, gastrointestinal, musculoskeletal, endocrine, and lymphoid systems, particularly in older adults. Regarding diagnosis, RT-PCR is the gold standard for detecting COVID-19, though it requires specialized equipment, skilled personnel, and considerable time to produce results. To address these limitations, artificial intelligence in imaging and microfluidics technologies offers promising alternatives for diagnosing COVID-19 efficiently. Pharmacological and non-pharmacological strategies are effective in mitigating the persistent impacts of COVID-19. These strategies enhance immunity in post-COVID-19 patients by reducing cytokine release syndrome, improving T cell response, and increasing the circulation of activated natural killer and CD8 T cells in blood and tissues. This, in turn, alleviates symptoms such as fever, nausea, fatigue, muscle weakness, and pain. Vaccines, including inactivated viral, live attenuated viral, protein subunit, viral vectored, mRNA, DNA, and nanoparticle vaccines, significantly reduce the adverse long-term effects of the virus. However, no vaccine has been reported to provide lifetime protection against COVID-19. Consequently, protective measures such as physical distancing, mask usage, and hand hygiene remain essential strategies. This review offers a comprehensive understanding of the persistent effects of COVID-19 on individuals of varying ages, along with insights into diagnosis, treatment, vaccination, and future preventative measures against the spread of SARS-CoV-2.

One of the common hazards and issues in meteorology and agriculture is the problem of frost, chilling or freezing. This event occurs when the minimum ambient temperature falls below a certain value. This phenomenon causes a lot of damage to the country, especially Fars province. Solving this problem requires that, in addition to predicting the minimum temperature, we can provide enough time to implement the necessary measures. Empirical methods have been provided by the Food and Agriculture Organization (FAO), which can predict the minimum temperature, but not in time. In addition to this, we can use machine learning methods to model the minimum temperature. In this study, we have used three methods Gated Recurrent Unit (GRU), Temporal Convolutional Network (TCN) as deep learning methods, and Gradient Boosting (XGBoost). A customized loss function designed for methods based on deep learning, which can be effective in reducing prediction errors. With methods based on deep learning models, not only do we observe a reduction in RMSE error compared to empirical methods but also have more time to predict minimum temperature. Thus, we can model the minimum temperature for the next 24 hours by having the current 24 hours. With the gradient boosting model (XGBoost) we can keep the prediction time as deep learning and RMSE error reduced. Finally, we experimentally concluded that machine learning methods work better than empirical methods and XGBoost model can have better performance in this problem among other implemented.

Depression is a common yet serious mental disorder that affects millions of U.S. high schoolers every year. Still, accurate diagnosis and early detection remain significant challenges. In the field of public health, research shows that neural networks produce promising results in identifying other diseases such as cancer and HIV. This study proposes a similar approach, utilizing machine learning (ML) and artificial neural network (ANN) models to classify depression in a student. Additionally, the study highlights the differences in relevant factors for race subgroups and advocates the need for more extensive and diverse datasets. The models train on nationwide Youth Risk Behavior Surveillance System (YRBSS) survey data, in which the most relevant factors of depression are found with statistical analysis. The survey data is a structured dataset with 15000 entries including three race subsets each consisting of 900 entries. For classification, the research problem is modeled as a supervised learning binary classification problem. Factors relevant to depression for different racial subgroups are also identified. The ML and ANN models are trained on the entire dataset followed by different race subsets to classify whether an individual has depression. The ANN model achieves the highest F1 score of 82.90% while the best-performing machine learning model, support vector machines (SVM), achieves a score of 81.90%. This study reveals that different parameters are more valuable for modeling depression across diverse racial groups and furthers research regarding American youth depression.